Description

Product Overview

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid mitochondrial-derived peptide (MDP) that plays a critical role in metabolic regulation. Unlike nuclear-encoded peptides, MOTS-c is encoded within the mitochondrial genome, making it a unique research tool for studying mitochondrial-nuclear communication and metabolic health.

Key Benefits

✅ Enhances insulin sensitivity and glucose uptake
✅ Promotes fatty acid oxidation and metabolic flexibility
✅ Activates AMPK pathway (key metabolic regulator)
✅ Protects against age-related metabolic decline
✅ Increases energy expenditure
✅ Supports mitochondrial function and biogenesis
✅ May improve exercise capacity and endurance

Research Data

Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Molecular Weight: 2,174.6 g/mol
Half-Life: ~2-3 hours (subcutaneous)
Administration: Subcutaneous or intramuscular injection

Storage & Handling

Lyophilized powder: store at -20°C for long-term, 2-8°C short-term. After reconstitution with bacteriostatic water, refrigerate and use within 14-21 days. Protect from light. Do not shake — swirl to mix.

Stacking Suggestions

Research protocols frequently study MOTS-c in combination with other metabolic peptides such as AOD-9604, SLU-PP-332, and NAD+ for comprehensive metabolic and mitochondrial research applications.

Quality Assurance

🔬 HPLC verified >98% purity. Third-party independent laboratory tested. Full Certificate of Analysis available in the Lab Report tab on this product page.

Important Notice

⚠️ For laboratory research use only. This product is a research chemical intended for in-vitro studies. Not for human, animal, or veterinary use. Follow all applicable laboratory safety guidelines.